种族气候对愿意参加临床研究的意愿
Sanaz Dabiri1, Rema Raman2, Linda B Cottler3
1Sol Price Schaeffer Center &, Alzheimer's Therapeutic Research Institute, University of Southern California, Los Angeles, CA, USA. sanazdab@usc.edu.
Journal of racial and ethnic health disparities
|July 7, 2025
概括
种族气候因素,如警察枪击和社会脆弱性,与非裔美国人加入临床研究的意愿下降有关. 解决这些社会生态问题对于改善参与研究的多样性至关重要.
科学领域:
- 健康差异研究 研究健康差异研究
- 临床试验招聘工作人员
- 公共卫生中的社会生态模型
背景情况:
- 美国在健康状况方面存在显著的种族和民族差异,特别是影响非洲裔美国人与白人相比.
- 招募非裔美国人社区进行临床研究,尽管存在这些健康结果差异,但仍面临着持续的挑战.
研究的目的:
- 检查地理区域的种族气候与参与临床研究的意愿之间的联系.
- 调查警方枪击事件,社区脆弱性和对研究机构的信任等因素如何影响参与.
- 应用社会生态模型框架来理解社区参与临床研究.
主要方法:
- 来自佛罗里达大学HealthStreet登记处关于社区对临床研究参与的看法数据的分析.
- 将注册数据与致命遭遇警察枪击数据以及县和邮政编码级别的社会脆弱性指数对齐.
主要成果:
- 较高的警察枪击率与非洲裔美国成年人参与涉及药物,遗传样本和医疗设备的研究的意愿降低有显著关联.
- 社区中增加的社会脆弱性与参与临床研究的意愿降低相关.
- 该研究包括大多数女性 (64%) 参与者,56.2%的参与者认定为黑人/非裔美国人,平均年龄为43.01岁.
结论:
- 社会生态因素对非裔美国人社区参与临床研究的贡献尚不清楚.
- 调查结果强调了解决种族气候和社会脆弱性的必要性,以加强社区参与.
- 改善这些因素对于减少临床研究中的多样性差距和实现健康公平至关重要.
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