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Updated: Sep 16, 2025

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认知障碍在轻度至重度SARS-CoV-2感染2年后,在一项基于人群的研究中,与匹配对比组进行了对比

Natália Araújo^1,2, Isa Silva³, Patrícia Campos^3,4

¹EPIUnit ITR, Instituto de Saúde Pública da Universidade do Porto, Porto, Portugal. natalia.araujo@ispup.up.pt.

Scientific reports

|July 7, 2025

概括

在SARS-CoV-2感染2年后的认知障碍在住院COVID-19幸存者和非住院感染者中比未感染群体更为普遍. 早期诊断和治疗对于COVID-19幸存者至关重要.

科学领域:

神经学神经学
传染性疾病传染性疾病
公共卫生公共卫生

背景情况:

COVID-19的长期认知后果是一个越来越令人担忧的问题.
有限的研究已经研究了感染后一年以上的认知功能.
了解持续性认知缺陷对于患者护理和公共卫生战略至关重要.

研究的目的:

为了确定SARS-CoV-2感染后两年认知障碍的患病率.
为了比较住院COVID-19幸存者的认知障碍与未感染的住院患者.
为了比较非住院COVID-19幸存者的认知障碍与非住院未感染者的认知障碍.

主要方法:

来自马托辛霍斯当地卫生部门的参与者回顾性选择 (2020年3月 - 2021年2月).
建立了四个组:住院COVID-19,住院未感染者,非住院COVID-19和非住院未感染者.
使用蒙特利尔认知评估 (MoCA) 和全面的神经心理评估来评估认知功能.

主要成果:

住院COVID-19幸存者 (19.1%) 的认知障碍明显高于未感染住院的患者 (6.8%).
非住院感染者 (10.7%) 的认知障碍高于非住院未感染者 (3.2%).
调整后的几率比率表明,在两个感染群体中,认知障碍的风险显著增加.

结论:

感染后两年,早期大流行时期的COVID-19幸存者表现出更高的认知障碍患病率.
对于COVID-19幸存者来说,需要及时诊断和治疗认知障碍的具体干预措施.
这些发现强调了SARS-CoV-2感染的长期神经影响.

关键词:

在 COVID-19 疫情中,认知障碍认知障碍是一种认知障碍.神经心理学评估神经心理学评估这是一种SARS-CoV-2感染.

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