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在正牙热塑性材料中的时间依赖的微生物组动态:比较PETG和TPU

Tianyi Gao¹, Jieyu Yun¹, Yage Zheng¹

¹Department of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China.

Clinical oral investigations

|July 7, 2025

概括

聚乙烯二甲酸甘醇 (PETG) 调整剂显著降低了唾液pH值和改变了口腔微生物组,而热塑性聚氨 (TPU) 调整剂显示了延迟的pH值变化和明显的微生物变化,长时间的磨损.

科学领域:

口腔微生物学口腔微生物学
生物材料科学是生物材料的科学.
ортодонтические 材料 ортодонтические 材料

背景情况:

ортодонтические对齐器越来越多地用于牙直.
在对齐器中使用的材料,如热塑性聚氨 (TPU) 和聚乙烯二甲糖醇 (PETG),可能会影响口腔环境.
了解这些材料对口腔微生物群和唾液pH的影响对于患者的健康至关重要.

研究的目的:

为了比较TPU和PETG对齐剂对口腔微生物群和唾液pH的影响.
为了研究在正义牙科治疗期间与不同对齐器材料相关的微生物转移和pH值变化.

主要方法:

十名参与者在24小时内穿着TPU和PETG对齐器.
从调整器和斑块中收集的唾液和微生物样本是在五个时间点收集的.
使用16S rRNA测序分析微生物组成和多样性;测量唾液pH值.

主要成果:

PETG对齐器在磨损早期显著降低了唾液pH值 (T4).
用PETG (T8) 观察到斑块中的微生物转移比使用TPU (T12-T24) 早.
在24小时内,TPU对齐器显示了特定细菌 (Veillonella,Actinomyces,Fusobacterium) 的减少,而PETG增加了Streptococcus和Fusobacterium.

结论:

与TPU对齐器相比,PETG对齐器更快地影响唾液pH和斑块微生物组合.
在长时间的磨损过程中,TPU对齐器会诱导明显的微生物变化.
材料选择和清洁方案可能需要根据微生物影响进行个性化.

关键词:

16S R Rna 在线播放清晰的对齐器清晰的对齐器牙科牙科是指牙科的专业.口腔微生物组是口腔的微生物组.矯正牙科矯正牙科是一種矯正牙科.热塑性材料是一种热塑性材料.

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