螺旋杆菌螺旋杆菌感染是否会影响袖子胃切除术后的反流症状? 使用患者报告结果指标 (PROM) 的试点研究
Isabella Amaniera1, Nicole L Petcka1, Varnette Robinson2
1Department of Surgery, Emory University School of Medicine, 550 Peachtree Street Northeast, Medical Office Tower, 7th Floor, Atlanta, GA, 30308, USA.
Surgical endoscopy
|July 7, 2025
概括
螺旋杆菌 (HP) 感染与袖子胃切除术 (SG) 后胃肠道症状的恶化有关. 阳性HP患者经历了手术后反流,胀气和吐的增加.
科学领域:
- 胃肠病学 胃肠病学
- 腹部外科 腹部外科
- 传染性疾病 传染性疾病
背景情况:
- 在代谢和减肥手术 (MBS) 后,Helicobacter pylori (HP) 感染对胃肠道症状的影响尚不清楚.
- 虽然袖子胃切除术 (SG) 已知可能会恶化反流,但关于HP在SG后的影响的具体数据有限.
研究的目的:
- 调查手术前HP感染和手术后胃肠道症状之间的关联在接受SG的患者中.
- 为了比较HP阳性和HP阴性SG患者之间的反流和与饮食相关的 (ER) 症状.
主要方法:
- 一项回顾性横截面研究分析了2023年2月至2024年12月期间从GS患者获得的患者报告结果指标 (PROM).
- 手术前的HP状况通过食道胃二透镜和活检得到证实.
- 胃食道逆流病与健康相关的生活质量 (GERD-HRQL) 和BODY-Q饮食模块被用于评估症状.
主要成果:
- 与HP阴性患者相比,HP阳性患者报告了与饮食相关的 (ER) 症状 (较低的BODY-Q得分) 显著恶化.
- 在HP阳性队列中观察到膨胀和吐的频率增加.
- 阳性HP患者的GERD-HRQL得分显着更高,表明反流更严重,并且在饭后报告更多的胃灼热.
结论:
- 肝炎感染与SG患者的较差结果有关,特别是反流增加和与饮食相关的症状,如胀气和吐.
- 在HP阳性患者中,更高的GERD-HRQL得分表明对反流相关症状有显著影响.
- 建议对更大,更多样化的群体进行进一步的研究,以探索HP在MBS结果中的作用.
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