在类风湿性关节炎中使用的测量仪器的最小重要差异:范围审查
Sally Yaacoub1, Anas El Zouhbi2, Michella Abi Zeid Daou3
1Clinical Research Institute, American University of Beirut Medical Center, Beirut, Lebanon.
BMC rheumatology
|July 7, 2025
概括
本研究提出了对类风湿性关节炎结果措施的最小重要差异 (MID) 估计. 结果显示了仪器MID估计的变化,影响了临床决策.
科学领域:
- 类风湿病学 类风湿病学
- 临床结果测量临床结果测量
- 卫生经济学 卫生经济学
背景情况:
- 连续变量经常用于测量类风湿性关节炎的结果.
- 确定最小重要的差异 (MID) 对于解释这些测量结果的临床意义至关重要.
- 有效的MID估计对于临床决策和风湿性关节炎的指导方针开发至关重要.
研究的目的:
- 编制和呈现最少重要的差异 (MID) 估计,用于仪器测量风湿性关节炎研究的结果.
- 为了解类风湿性关节炎变化的临床意义提供资源.
主要方法:
- 进行了对MID估计的原始研究报告的范围审查,用于类风湿性关节炎结局仪器.
- 研究使用分布或基方法进行MID估计.
- 从35项符合条件的研究中提取数据,包括72种仪器的144个MID估计.
主要成果:
- 审查确定了144个最小重要的差异 (MID) 估计在类风湿性关节炎中使用的72种仪器.
- 身体功能,疾病活动,健康状况和疲劳是最常见的测量构造.
- 主要使用的是基于的方法 (72%),健康评估问卷残疾指数是最常见的报告工具.
结论:
- 确定了大量的风湿性关节炎测量仪器的最小重要差异 (MID) 估计.
- 在同一仪器的MID估计中观察到显著的变化,无论是在不同研究中还是在不同研究中.
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