右心室心声学参数与心力衰竭中的HFA-PEFF得分与保存的射出小部分之间的关联
Hacı Ali Kürklü1, Türkan Seda Tan2, Nil Özyüncü2
1Department of Cardiovascular Medicine, Ankara Etlik City Hospital, Ankara, Türkiye.
概括
HFA-PEFF得分,用于心力衰竭与保存喷射分数 (HFpEF),与较差的右心室 (RV) 功能有关. 较高的得分与较差的RV心声学参数相关,这表明RV评估增加了预后价值.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心脏衰竭研究研究
背景情况:
- 保存喷射分数 (HFpEF) 的心力衰竭占心力衰竭住院病例的50%以上.
- 该HFA-PEFF算法有助于HFpEF诊断和预后.
研究的目的:
- 调查HFpEF患者的HFA-PEFF得分和右心室 (RV) 声心谱参数之间的相关性.
- 探索HFpEF中RV功能的预后影响.
主要方法:
- 追溯分析127名HFpEF患者的胸前心声学 (TTE) 数据.
- 根据HFA-PEFF得分 (0-6) 将预后风险划分为低,中,高风险组.
- 使用TAPSE,S'速度和RVFW GLS评估RV功能;通过ANOVA和斯皮尔曼相关性进行统计分析.
主要成果:
- 在高HFA-PEFF得分的患者中观察到TAPSE和RVFW GLS的显著下降.
- 在HFA-PEFF得分和RVFW GLS之间存在中度负相关性 (r = 0.50,P < 0.001).
- 在HFA-PEFF得分和TAPSE之间发现轻微负相关性 (r = -0.35,P < 0.001).
结论:
- 在HFpEF患者中,RV参数 (RVFW 2D GLS,TAPSE) 的恶化显而易见,根据HFA-PEFF得分确定HFpEF患者的预后不佳.
- 将RV参数纳入HFpEF诊断和预后策略可能会提高临床效用.
- RV评估为HFpEF预后提供了有价值的见解.
相关概念视频
01:17Pathophysiology of Heart Failure
1.9K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.9K
01:29Heart Failure II: Pathophysiology
51
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
51
01:26Heart Failure III: Clinical Manifestations
52
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
52
01:30Heart Failure V: Medical Management
29
Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
29
01:30Heart Failure IV: Classification and Diagnostic Evaluation
38
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
38
01:27Heart Failure I: Introduction
62
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
62