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Updated: Sep 16, 2025

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双异质性的抗癌疗效 (iii) 复合物与二替代的烯酸连接物

Suvasmita Behera1,2, Kahnu Charan Pradhan1,2, Sahadev Barik3

  • 1P.G. Dept. of Chemistry, Utkal University Bhubaneswar Odisha 751004 India snpal@utkaluniversity.ac.in.

RSC advances
|July 8, 2025
PubMed
概括

新的 (Ir1-Ir3) 复合物通过诱导癌细胞亡和增加癌细胞中的活性氧物种 (ROS) 来表现出强烈的抗癌活性. 复合物Ir2的疗效与西斯普拉丁相当,突出了癌症治疗的潜力.

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Bromination and chlorination of aromatic rings by electrophilic aromatic substitution reactions are easily achieved, but fluorination and iodination are difficult to achieve. Fluorine is so reactive that its reaction with benzene is difficult to control, resulting in poor yields of monofluoroaromatic products. To address this, Selectfluor reagent is used as a fluorine source in which a fluorine atom is bonded to a positively charged nitrogen.
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