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成功的转换手术为不可切割的微卫星不稳定性-高胰腺尾部癌症在布罗利祖马布治疗后
Nobuhiro Harada1, Masanao Kurata1, Yasuji Seyama1
1Department of Hepato-Biliary-Pancreatic Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.
Surgical case reports
|July 8, 2025
概括
布罗利祖马布成功治疗了一种罕见的不可切除的微卫星不稳定性高 (MSI高) 胰腺癌病例,使转化手术成为可能. 这突出了免疫疗法.
科学领域:
- 在瘤学瘤学.
- 免疫治疗是一种免疫疗法.
- 胰腺癌研究研究
背景情况:
- 胰腺癌通常具有微卫星不稳定性-高 (MSI-高) 状态的低患病率 (<1%).
- 布罗利祖马布已被批准用于高MSI的癌症,这些癌症对化疗无反应.
- 这个案例探讨了pembrolizumab在一种罕见的MSI高的胰腺癌亚型中的疗效.
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