植物提取物Vatica diospyroides的抗菌潜力:针对水产养殖中的各种病原体
Juthatip Yooklaen1,2, Theera Srisawat1,2, Luu Tang Phuc Khang3
1Department of Agricultural Science and Technology, Faculty of Science and Industrial Technology, Prince of Songkla University, Surat Thani Campus, Surat Thani, Thailand.
International journal of microbiology
|July 8, 2025
概括
Vatica diospyroides花提取物显示出针对各种细菌菌株的显著抗菌潜力. 这项研究探讨了它的机制,揭示了剂量和时间依赖的影响和结构性细胞损伤.
科学领域:
- 药理学和微生物学 药理学和微生物学
- 自然产品化学 自然产品化学
背景情况:
- 瓦蒂卡二氧化,一个特有Dipterocarpaceae物种,已知有药用特性.
- 关于其花提取物的抗菌活性存在有限的研究.
- 这项研究解决了了解V. diospyroides花提取物的抗菌机制的差距.
研究的目的:
- 为了研究Vatica diospyroides花提取物的抗菌机制.
- 为了评估这些提取物对四种不同的细菌菌株的疗效.
- 为了确定提取物对细菌细胞的剂量和时间依赖的影响.
主要方法:
- 从V. diospyroides花中制备了乙提取物.
- 使用井盘扩散,MIC和MBC测试来评估抗菌活性.
- 细菌细胞反应通过流细胞计和扫描电子显微镜分析.
主要成果:
- 抑制区范围从6.33到17.66毫米.
- 最低抑制度 (MIC) 值各不相同,其中V. parahaemolyticus是最容易受到影响的 (62.5μg/mL).
- 流细胞计和SEM证实了剂量和时间依赖的抗菌作用,包括结构性细胞损伤.
结论:
- 瓦蒂卡二氧化的花提取物表现出有希望的广泛的抗菌活性.
- 提取物对细菌活力和结构表现出剂量和时间依赖的影响.
- 对V. diospyroides花提取物的进一步研究可能会导致新的抗菌剂.
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