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Updated: May 13, 2026

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系统的泛癌分析确定PKNOX1作为潜在的预后和免疫生物标志物及其功能验证

Kan Liu1, Yongkang Xu1, Ye Mao1

  • 1Department of Oncology, The Second Affiliated Hospital, Jiangxi Medcical College, Nanchang University, Nanchang, China.

Frontiers in immunology
|July 8, 2025
PubMed
概括

PBX/knotted1 homeobox 1 (PKNOX1) 在大多数癌症中表达很高,与预后不佳相关,并促进瘤生长. 这项研究确定PKNOX1是各种癌症的潜在预后和免疫生物标志物,包括HCC和乳腺癌.

关键词:
肝癌和乳腺癌中的一个.在PKNOX1中,PKNOX1是PKNOX1中的一个.免疫透 免疫透是什么?胰腺癌是一种癌症.预后生物标志物 预后生物标志物

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NF-κB-dependent Signaling Pathway02:26

NF-κB-dependent Signaling Pathway

The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
NF-κB-dependent Signaling Mechanism
The heterodimer of NF-κB...