美国成年人肥胖指标和视网膜病变之间的关联:NHANES 2005-2008年
Chuan-Xi Wang1, Miao Kuang1,2, Jing-Jing Hou1
1Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Frontiers in nutrition
|July 8, 2025
概括
增加的肥胖指标,如腰与身高的比 (WHtR) 与较高的视网膜病变风险有关. 在这项研究中,体重调整后腰部指数 (WWI) 显示出最强的预测值.
科学领域:
- 眼科医生 眼科 眼科
- 公共卫生 公共卫生
- 内分泌学 在内分泌学.
背景情况:
- 肥胖对视网膜健康构成重大风险.
- 关于特定的肥胖指标及其与视网膜病变相关的研究有限.
- 这项研究旨在澄清各种肥胖指标与视网膜病变之间的关系.
研究的目的:
- 调查多种肥胖指标与视网膜病变的存在之间的关联.
- 确定不同肥胖指标对视网膜病变的预测值.
- 探索这种关联中潜在的非线性关系和子组变异.
主要方法:
- 利用了来自国家健康和营养检查调查 (NHANES) 的数据.
- 采用加权多因素后勤回归和子组分析.
- 适用于非线性分析的受限立方线 (RCS) 和用于预测价值评估的接收器运行特征 (ROC) 曲线.
主要成果:
- 在身体圆度指数 (BRI),度指数 (CI),WHtR,三重体质指数 (TMI),第一次世界大战和与视网膜病变的身体质量指数 (BMI) 之间发现了积极的关联.
- RCS证实了BRI,CI,WHtR,TMI和WWI的线性相关性,但BMI没有.
- 第一次世界大战证明了视网膜病变的最高预测能力,在人口亚组中没有观察到显著的相互作用.
结论:
- 多种肥胖指标的高水平与患视网膜病变的可能性增加有关.
- 体重调整腰部指数 (WWI) 成为预测视网膜病变风险的关键指标.
- 这些发现强调了监测肥胖指标对于早期检测和预防视网膜病变的重要性.
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