复杂区域疼痛综合征 (CRPS) 患者的认知功能
S Liesto1,2, T Aho1, S K Jääskeläinen3
1Dept. of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
European journal of pain (London, England)
|July 8, 2025
概括
30%的复杂区域疼痛综合征 (CRPS) 患者表现出认知能力下降. 神经心理学评估对于CRPS诊断和康复计划至关重要,以有效地解决认知障碍.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 康复医学 康复医学 康复医学
背景情况:
- 复杂区域性疼痛综合征 (CRPS) 呈现出各种症状,包括疼痛,感觉,运动和热量变化,以及报告的认知困难.
- CRPS是一种复杂的,致残的疾病,通常源于中枢神经系统的神经可塑性.
- 以前的研究对CRPS的认知领域的探索是有限的,不包括横向认知和身体感知.
研究的目的:
- 调查诊断为复杂区域性疼痛综合征 (CRPS) 类型1和2的患者的神经心理状况.
- 为了确定CRPS患者认知能力下降的患病率.
- 探索CRPS中心理因素和认知表现之间的关系.
主要方法:
- 对54名CRPS患者进行了神经心理检查,使用一系列测试来评估智力,记忆,执行功能和注意力.
- 在至少三项测试中,认知能力下降被定义为与健康芬兰人口相比低于-0.67 SD的表现.
- 经过验证的问卷评估了失眠,抑郁,疼痛灾难化,弹性,功能障碍和焦虑.
主要成果:
- 30%的CRPS患者的显著亚组显示出客观认知能力下降.
- 增加疼痛灾难化与Trail Making Test Part A的表现较差相关.
- 在CRPS 1和CRPS 2患者之间,以及左侧和右侧注意力测试之间,没有观察到认知功能的显著差异.
结论:
- 在30%的CRPS患者中,认知能力下降是普遍存在的,这强调了在诊断和康复中需要进行神经心理评估的必要性.
- 心理因素,如疼痛灾难化,可能会不成比例地影响主观认知投诉对客观测试表现.
- 了解CRPS患者的认知特征对于定制有效的多学科康复策略至关重要.
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