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Updated: Sep 16, 2025

3D Multicolor DNA FISH Tool to Study Nuclear Architecture in Human Primary Cells
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3D Multicolor DNA FISH Tool to Study Nuclear Architecture in Human Primary Cells

Published on: January 25, 2020

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细胞身份的转录程序和p53诱导的应激反应与空间基因组组织的独特特征有关

Gony Shanel1, Tsung-Han S Hsieh2, Claudia Cattoglio2,3

  • 1Department of Human Molecular Genetics and Biochemistry, Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel.

Nucleic acids research
|July 8, 2025
PubMed
概括

空间基因组组织在细胞身份和应激反应之间存在差异. 细胞类型特异性相互作用与基因表达相关,但压力诱导的变化没有,支持接触独立机制.

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