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机械外部双管辅助装置的演示,用于复苏性胸腔切除术

Kristof Sarosi¹, Thomas Kummer², Thomas Roesgen²

¹Department of Mechanical and Process Engineering, Institute of Fluid Dynamics, ETH Zurich, Zurich, Switzerland. ksarosi@ethz.ch.

Cardiovascular engineering and technology

|July 8, 2025

概括

一种新型的外部双心室辅助装置 (BiVAD) 显示出在复苏胸切除术期间改善存活率的前景. 在最初的测试中,这种BiVAD系统实现了足够的心脏输出,并降低了与手动按摩相比的峰值心室压力.

科学领域:

生物医学工程生物医学工程
心血管研究研究心血管研究
紧急医疗紧急医疗

背景情况:

复苏胸切除术是危及生命的胸部创伤或心脏骤停的关键高风险手术.
目前的成功率有限,即使有专家干预.
开放式心脏按摩是标准的,但有显著的缺点.

研究的目的:

调查外部双心室辅助装置 (BiVAD) 作为在复苏胸腔切除术期间开放心脏按摩的替代品.
评估BiVAD保持充足心脏输出和生理压力的能力.
探索在危急情况下改善患者生存的潜力.

主要方法:

开发了一个3D打印的BiVAD贴片系统,旨在为直接的心脏附着和快速应用而设计.
该系统在体外液压模拟循环中使用心脏模型进行了测试.
通过比较BiVAD激活与手动心脏按摩,测量心室压力和流量,来评估性能.

主要成果:

BiVAD系统实现了1.5L/分钟的目标心脏输出,这对生存至关重要.
与60bpm的标准心脏手部按摩相比,BiVAD显著降低了两个心室的峰值心室压力.
流量和压力数据证明了BiVAD在模拟的关键场景中的有效性.

结论:

BiVAD系统显示了在复苏性胸腔切除过程中提供有效的心脏支持的潜力.
它可以达到足够的心力输出,同时减轻过度压力,在初步模型中表现优于手动按摩.
这种BiVAD技术的进一步开发可能会显著提高接受这种紧急手术的患者的治疗结果.

关键词:

有助于循环的辅助循环.心脏输出的心脏输出.心肺复苏是心肺复苏的方法之一.紧急的心脏外科手术是什么进行复苏性胸腔切除术 (resuscitative thoracotomy).腹腔室辅助器件设备可以帮助.

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