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增长因子向TSC复合体发出信号以调节mTORC1的演变

Kun Wang1,2, Sophie E Lockwood1,2, Brendan D Manning1,2

  • 1Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.

Science signaling
|July 8, 2025
PubMed
概括

拉巴胺素 (mTOR) 复合体1 (mTORC1) 途径的机械性标调节了细胞生长. 它通过生长因子的调节与复杂的生物进化,涉及TSC2蛋白的非结构循环.

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