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艾滋病毒感染者的补充和替代药物:来自CAMPER研究的结果
Lolita Sasset1, Maria Mazzitelli1, Mattia Trunfio2,3
1Infectious and Tropical Diseases Unit, University Hospital of Padua, Padua, Italy.
International journal of STD & AIDS
|July 8, 2025
概括
补充/替代医学 (CAM) 在艾滋病毒感染者 (PLWH) 中很常见,近40%的人使用它. 使用CAM并没有对治疗坚持,免疫反应或生活质量产生负面影响.
科学领域:
- 艾滋病毒 医学 艾滋病毒 医学
- 公共卫生 公共卫生
- 综合医学是一个整体的医学.
背景情况:
- 在艾滋病毒感染者 (PLWH) 中,使用补充/替代医学 (CAM) 的流行率很高.
- 了解CAM患病率及其对PLWH健康结果的影响对于综合护理至关重要.
研究的目的:
- 确定艾滋病毒感染者中CAM使用的流行率 (PLWH).
- 调查CAM对PLWH免疫病毒反应,治疗坚持和生活质量 (QoL) 的影响.
- 确定与PLWH中CAM使用相关的因素.
主要方法:
- 进行了一项多中心,横截面的观察性研究.
- 548名接受联合抗逆转录病毒疗法 (cART) 的PLWH完成了衡量补充和替代医学使用的国际问卷 (I-CAM-Q).
- 描述性统计和多变量后勤回归被用于分析.
主要成果:
- 38.5%的参与者报告使用CAM,主要是维生素和食补充剂 (64.2%).
- 使用CAM与特定的人口因素有关,包括种族,艾滋病毒感染途径,HCV状态,教育水平,血不可检测性和心血管疾病.
- 在CAM用户和非用户之间没有观察到免疫病毒反应,治疗坚持或QOL的显著差异.
结论:
- 在PLWH中,CAM的使用普遍存在,并且似乎不会对治疗疗效或临床结果产生不利影响.
- 人口因素显著影响CAM在这个人群中的使用.
- 医疗保健提供者应与PLWH讨论CAM使用情况,以确保提供知情和安全的综合护理.
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