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针对耐药结核病:替代酸胺的佐醇作为抑制II型NADH脱酶的杀菌剂

Pallavi Saha1, Shashikanta Sau2, Nitin Pal Kalia2

  • 1Department of Pharmaceutical Engg. and Tech, IIT-Banaras Hindu University, Varanasi, UP 221005, India.

Bioorganic chemistry
|July 8, 2025
PubMed
概括

新型西醇衍生物通过抑制II型NADH脱酶,这是Mycobacterium tuberculosis中关键的能量产生酶,表现出强大的抗结核活性. 这些化合物对耐药菌株有效,并显示出强大的安全性.

关键词:
佐提亚 (Benzothiazole) 是一种一种耐药结核病的治疗方法结核病菌菌菌的结核病菌的结核病菌.单核酸多形态的单核酸多形态第二种类型的NADH脱酶酶.电子传输链中的电子传输链.

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