在前列腺癌放射治疗中使用超声波评估膀体积的前性研究:与形束计算断层扫描 (CBCT) 的比较
B Bąk1, K Kaczmarek2, D Radoła1
1Department of Electroradiology, University of Medical Sciences, Poznań, Poland; Radiotherapy Department II, Greater Poland Cancer Center, Poznań, Poland.
Radiography (London, England : 1995)
|July 8, 2025
概括
超声波精确测量前列腺癌放射治疗中的膀体积,为每日监测和减少辐射暴露提供了形束计算机断层扫描 (CBCT) 的非侵入性替代方案.
科学领域:
- 辐射瘤学 辐射瘤学
- 医疗成像医学成像
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 持续的膀填充对于优化剂量递送和尽量减少前列腺癌放射治疗中的毒性至关重要.
- 进行了对超声波 (US) 精度的前性评估,以评估膀体积与圆束计算机断层扫描 (CBCT) 相比.
研究的目的:
- 在接受放射治疗的前列腺癌患者中,评估超声波 (US) 在测量膀体积的准确性,与形光束计算机断层扫描 (CBCT) 相比.
- 评估超声波作为日常膀体积监测的非侵入性工具的潜力.
主要方法:
- 接受VMAT的22名前列腺癌患者接受了600-800毫升的水以填充膀.
- 在CBCT成像之前,每天进行超声波测量 (USGRT).
- 放射治疗师在CBCT扫描上对膀进行了轮,以2毫米的边际计算体积.
主要成果:
- 进行了1650次超声波测量,显示了与CBCT的强烈相关性 (r = 0.888,p < 0.001).
- 美国的平均膀体积为286毫升 (SD ±118) 与CBCT的241毫升 (SD ±124).
- 在USGRT和V2CBCT之间发现了显著的相关性 (r = 0.84,p < 0.0001).
结论:
- Echoson®膀扫描仪显示出作为日常膀体积监测的非侵入性方法的潜力.
- 超声波可以减少每日CBCT的辐射暴露,并简化治疗工作流程.
- 膀填充方案适用于所有临床可接受误差为17%的患者.
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