具有统计意义的III期瘤学试验的可复制性:一个In Silico元流行病学分析

Alexander D Sherry1, Pavlos Msaouel2, Avital M Miller3

  • 1Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Radiation Oncology, Mayo Clinic, Rochester, MN, USA.

European journal of cancer (Oxford, England : 1990)
|July 8, 2025
PubMed
概括

在III期瘤学试验中的统计学显著性 (P ≤ 0.05) 并不能保证可重现的效果. 先进的建模显示P=0.05的复制概率很低,强调仅仅是显著性并不保证可靠的发现.

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