胃肠道癌的常见危险因素:叙述性综述
Ehsan Allah Kalteh1, Mohammad Hassan Lotfi1, Hossein Akhondi1
1Center for Healthcare Data Modeling, Departments of Biostatistics and Epidemiology, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
概括
由于饮食不良,不活动和吸烟等因素,胃肠道癌症在全球范围内不断增加. 解决这些可修改的风险是减少癌症负担和改善健康结果的关键.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 胃肠道 (GI) 癌症是全球主要的健康负担,对发病率和死亡率作出重大贡献.
- 尽管医学取得了进展,但肠道癌的发病率仍在不断增加,这是由于风险因素的复杂相互作用所致.
- 了解这些多方面的风险因素对于有效的预防和管理策略至关重要.
研究的目的:
- 识别和综合关键的风险因素,有助于胃肠道癌症的发展和进展.
- 突出生活方式,环境,遗传和社会经济因素在肠道癌症病因学的相互作用.
- 为预防胃肠道癌症提供公共卫生干预,政策制定和健康教育倡议的信息.
主要方法:
- 这项研究采用了叙事审查方法.
- 从现有文献中确定并综合了关键的风险因素.
- 审查的重点是包括饮食,体育活动,肥胖,吸烟,酒精,感染,环境污染,压力和社会经济地位在内的因素.
主要成果:
- 确定的胃肠道癌的关键风险因素包括不健康的饮食,身体不活动,肥胖,吸烟,饮酒,感染 (例如,Helicobacter pylori),环境污染,慢性压力和社会经济差异.
- 强调这些多样化的风险因素在肠道癌的发展和进展中的协同作用.
- 强调早期检测和定制公共卫生干预措施的关键作用.
结论:
- 一个全面的,多部门的方法解决可修改的风险因素是必要的,以减少全球消化道癌的负担.
- 生活方式的修改和有针对性的公共卫生策略可以显著改善长期健康结果.
- 了解风险因素的相互联系为有效的预防和政策制定提供了关键的见解.
相关概念视频
02:59Cancer Prevention
6.3K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.3K
01:30Other Disorders of Digestive System
1.0K
The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
1.0K
01:25Factors Influencing Drug Absorption: Disease States and Pharmacology
823
Multiple disease states can significantly influence the oral drug absorption process by affecting blood flow and the functionality of the gastrointestinal (GI) system. Various GI diseases, including conditions that alter GI motility, such as diarrhea, decreased acid secretions (achlorhydria), and infections, have been associated with reduced drug absorption.
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
823
01:30Peptic Ulcer Disease I: Introduction
300
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
300
02:21Cancers Originate from Somatic Mutations in a Single Cell
13.0K
Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
13.0K
01:17Chronic Bowel Disorders: Introduction
541
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
541