Inés González-Castellano1,2, Aurora García-Dorado3, Armando Caballero1

  • 1Centro de Investigación Mariña, Universidade de Vigo, Vigo, Spain.

概括

由衰退性或过度主导性突变引起的内生繁殖负载,通过遗传漂移减少,特别是在小效应突变中. 虽然清除会去除衰退突变,但过度主导的突变会导致健康状况的持续下降.

相关概念视频

Hardy-Weinberg Principle01:49

Hardy-Weinberg Principle

Diploid organisms have two alleles of each gene, one from each parent, in their somatic cells. Therefore, each individual contributes two alleles to the gene pool of the population. The gene pool of a population is the sum of every allele of all genes within that population and has some degree of variation. Genetic variation is typically expressed as a relative frequency, which is the percentage of the total population that has a given allele, genotype or phenotype.
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Incomplete Dominance01:43

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Mutation, Gene Flow, and Genetic Drift

In a population that is not at Hardy-Weinberg equilibrium, the frequency of alleles changes over time. Therefore, any deviations from the five conditions of Hardy-Weinberg equilibrium can alter the genetic variation of a given population. Conditions that change the genetic variability of a population include mutations, natural selection, non-random mating, gene flow, and genetic drift (small population size).
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