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西部马类脑炎病毒与PCDH10受体的接触的结构基础

Shengjian Liang1, Yan Yang2, Yixiao Liu1

  • 1School of Basic Medical Sciences, Tsinghua University, Beijing, China.

Nature communications
|July 8, 2025
PubMed
概括

西方马脑炎病毒 (WEEV) 使用PCDH10作为受体,但一些菌株失去了这种能力. 这项研究揭示了WEEV-PCDH10结构,确定了关键的结合残留物,并为抗病毒开发提供了洞察力.

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