固体器官移植对老年男性和女性性功能障碍和不孕症的影响:基于索赔的研究
Obinna Obuekwe1, Haley Clark2, Gal Saffati3
1Department of Urology, Houston Methodist Hospital, Houston, TX, USA.
International journal of impotence research
|July 8, 2025
概括
固体器官移植 (SOT) 可能改善性健康,减少性功能障碍,特别是在男性中. 然而,SOT对所有器官类型的不孕症的影响有限.
科学领域:
- 移植医学 移植医学
- 性健康 性的健康
- 生殖医学 生殖医学
背景情况:
- 固体器官移植 (SOT) 对于恢复器官功能和延长存活至关重要.
- SOT对性功能障碍和不孕不育的影响仍未得到充分研究.
- 了解这些影响对于移植后的全面患者护理至关重要.
研究的目的:
- 评估性功能障碍和不孕不育在SOT前后的发生率.
- 在不同器官移植类型 (心脏,脏,肝脏,肺,胰腺) 中分析这些变化.
- 评估SOT对性别分层的性健康结果的影响.
主要方法:
- 使用TrinetX数据库进行回顾性队列研究.
- 包括过去20年来在美国接受SOT的64,932名成年患者.
- 使用ICD-10代码识别性功能障碍和不孕症;分析移植前和移植后的数据以减少风险.
主要成果:
- SOT与性功能障碍 (ARR 1.40%) 和不孕症 (ARR 0.10%) 的显著减少有关.
- 与女性相比,男性的性功能障碍 (ARR 2.11%) 减少得更大 (ARR 0.20%).
- 心脏,脏,肺和肝移植后,性功能障碍降低,但胰腺移植后没有降低;不孕不育的患病率在SOT类型之间没有显著差异.
结论:
- SOT可能会对性健康产生积极影响,特别是减少男性接受者的性功能障碍.
- SOT对性健康的好处因器官类型而异,对不孕不育的影响有限.
- 需要进一步的研究,以充分了解和管理移植受体的性健康问题.
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