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Updated: Sep 16, 2025

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生物物理要求,规范设计的微型蛋白质的高效内分体逃逸

Jonathan Giudice1, Daniel D Brauer1, Madeline Zoltek2

  • 1Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA.

Nature chemistry
|July 8, 2025
PubMed
概括

ZF5.3迷你蛋白使用pH触发的展开来逃脱内分泌体,与特定的脂质相互作用,将货物送到细胞质或细胞核. 这种机制对于其在细胞运输中的功能至关重要.

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