优化和评估基于盒子-Behnken设计的科尔奇辛补丁配方

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Updated: Sep 16, 2025

Optimization of Processing of Tiebangchui with Highland Barley Wine Based on the Box-Behnken Design Combined with the Entropy Method
09:12

Optimization of Processing of Tiebangchui with Highland Barley Wine Based on the Box-Behnken Design Combined with the Entropy Method

Published on: May 19, 2023

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Wenliang Dong1,2,3, Jiahao Feng1,2, Xiang Liu1,2

  • 1College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.

AAPS PharmSciTech
|July 8, 2025
PubMed
概括

研究人员使用BOX-Behnken设计 (BBD) 优化了胆固醇 (COL) 透皮贴片,以改善粘附和药物输送. 优化的贴片为口服COL提供了一个有希望的替代品,可能减少副作用.

关键词:
在体外浸透测试中进行透测试.在体外释放测试试验 (in vitro release testing) 进行.盒子背后的实验设计科尔奇辛 (Colchicine) 是一种可怕的药物.通过皮肤贴片的贴片.

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