沙特的临床实践指南,用于管理轴性脊柱关节炎疾病的管理
Hanan Al Rayes1, Nayef Al Ghanim2, Hajer Y Almudaiheem3
1Prince Sultan Military Medical City, Department of Medicine, Princess Nourah Bint Abdulrahman University, 7699 Ibn Abi Jaradah St, Al Sulaymaniyah, Riyadh, Saudi Arabia. alrayesh@hotmail.com.
Rheumatology and therapy
|July 8, 2025
概括
本指南提供了基于证据的建议,用于管理沙特阿拉伯的轴性脊柱关节炎 (axSpA). 它建议首先使用非类固醇抗炎药物 (NSAIDs),如果需要,再使用先进疗法.
科学领域:
- 类风湿病学 类风湿病学
- 临床实践指南 临床实践指南
- 脊椎关节炎管理管理
背景情况:
- 轴性脊椎关节炎 (axSpA) 是一种慢性炎症性疾病.
- 有效的管理策略对于患者的治疗结果至关重要.
- 沙特阿拉伯要求针对axSpA.有具体的,基于证据的临床指南.
研究的目的:
- 为沙特阿拉伯 axSpA 管理制定基于证据的临床实践指南.
- 为医生和政策制定者提供建议.
- 更新目前监测和治疗axSpA的最佳实践.
主要方法:
- 一个由14名专家组成的小组提出了45个关于axSpA管理的问题.
- 在PubMed,EMBASE和Cochrane图书馆 (2010-2024) 进行了系统的文献搜索.
- 在GRADE方法中,评估证据的确定性,通过专家投票 (>70%的同意) 完成建议.
主要成果:
- 发布了31份基于证据的建议和7份专家意见.
- 推非类固醇抗炎药物 (NSAIDs) 作为症状性 axSpA.的第一线治疗.
- 二线选择包括TNF抑制剂,IL-17抑制剂或JAK抑制剂;针对特定病例建议局部注射葡萄糖皮质激素.
结论:
- 该指南为沙特阿拉伯的成人 axSpA 护理提供了最新的,基于证据的建议.
- 这些指导方针旨在规范和改进axSpA的管理.
- 它们是该地区医疗保健专业人员的重要资源.
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