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Updated: Sep 16, 2025

Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation
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Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation

Published on: March 21, 2020

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最近在针对LRRK2治疗帕金森病的治疗方面取得的进展

Mahsa Karami1,2,3, Pantea Majma Sanaye2,3,4, Atousa Ghorbani3,5

  • 1Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Journal of translational medicine
|July 8, 2025
PubMed
概括

富含白素的重复激酶2 (LRRK2) 基因突变与帕金森病 (PD) 病原发生有关. 抑制LRRK2显示了治疗潜力,用于管理PD进展和开发诊断生物标志物.

关键词:
自自是一种自的过程.这是LRRK2线粒体功能障碍 线粒体功能障碍神经炎症是一种神经炎症.神经退行性疾病的神经退行性疾病这就是PROTAC.帕金森病是帕金森氏症的一种疾病.

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