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介酶干细胞和膝关节骨关节炎:一个文献计量分析

Linjin Lu¹, Haodong Liang¹, Huan Li²

¹The Affiliated Traditional Chinese Medicine Hospital, Guangzhou Medical University, Guangzhou, China.

|July 9, 2025

概括

中介细胞干细胞 (MSCs) 显示出治疗膝关节关节炎 (KOA) 的前景. 研究突出了MSC的有效性和机制,未来重点是用于KOA治疗的脂肪衍生MSC和外体.

科学领域:

再生医学是一种再生医学.
整形外科整形外科整形外科
干细胞生物学干细胞生物学

背景情况:

介质干细胞 (MSC) 具有自我更新和分化能力,这表明膝关节骨关节炎 (KOA) 治疗的巨大潜力.
在KOA治疗中MSC的应用是一个活跃的研究领域,越来越感兴趣.

研究的目的:

分析研究环境,确定关键主题,并预测未来使用MSCs治疗KOA的趋势.
为未来的研究方向和MSCs在管理KOA中的临床应用提供基础.

主要方法:

2012年至2022年间发表的1537项研究的图书统计分析,来自Web of Science核心集合.
使用Hiplot Pro和CiteSpace软件进行国家,机构,作者,关键词和参考文献的统计和视觉分析.
专注于关键词的共同出现和共同引用分析,以确定研究主题.

主要成果:

美国,中国和意大利是MSC对KOA的研究的主要贡献者.
关键的研究主题围绕MSCs在KOA.关节软骨治疗中的疗效和机制.
大量的引用数量 (41,916) 表明了这一领域的影响和兴趣.

结论:

MSCs在KOA治疗中具有相当大的临床潜力,广泛的研究证明了这一点.
了解MSC的临床疗效和机制仍然是研究的核心焦点.
未来的研究方向包括脂肪衍生的MSC,MSC衍生的外体,以及KOA中MSC应用的安全性评估.

关键词:

多国中心的MSCs.文献计量分析的分析膝盖骨关节炎膝盖骨关节炎介质细胞干细胞介质细胞干细胞

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