目前的洞察力和趋势在亚托皮炎和微生物群相互作用:一个系统的审查和文献分析分析
Zhongsong Zhang1,2, Rong Wang2, Mao Li1
1Department of Dermatovenereology, Clinical Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, China.
Frontiers in microbiology
|July 9, 2025
概括
对阿托皮性皮肤炎 (AD) 和微生物群的研究显示出显著的生长,突出的是皮肤和肠道微生物群.
科学领域:
- 皮肤病学 皮肤病学
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
- 图书统计学 图书统计学
背景情况:
- 亚托皮炎 (AD) 是一种常见的炎症性皮肤疾病.
- 免疫功能障碍,遗传学和环境都有助于AD.
- 皮肤和肠道微生物群在AD病变发生过程中发挥着至关重要的作用.
研究的目的:
- 绘制阿托皮性皮肤炎 (AD) 和微生物群相互作用的研究格局.
- 综合趋势,并确定未来的研究方向在AD和微生物群的研究.
- 通过系统性审查和文献计量分析,提供对AD微生物群研究的全面概述.
主要方法:
- 从Web of Science (2009-2024) 中对1,196篇文章进行了图书统计分析.
- 使用CiteSpace,VOSviewer和Biblioshiny进行数据分析.
- 评估出版趋势,地理贡献,机构产出和关键词演变.
主要成果:
- 研究在2016年之后激增,在2021年达到顶峰;美国在出版物和引用方面领先.
- 哥本哈根大学和过敏和临床免疫学杂志是最大的贡献者.
- 关键主题包括皮肤/肠道微生物组,金黄色葡萄球菌,肠-皮肤轴,以及对成年阿尔茨海默病,益生菌和FMT的新兴关注.
结论:
- 随着全球合作,阿尔茨海默病和微生物群的研究正在迅速扩大.
- 微生物失调和免疫调节是AD管理的核心.
- 这些发现支持精准医学,饮食干预和改善患者的治疗结果.
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