在非阻塞性冠状动脉患者中,心肌桥梁,动脉样硬化和之间的相互作用
Alexandra Bastiany1, Laurie-Anne Boivin-Proulx2, Tess E Allan3
1Department of Cardiology, Thunder Bay Regional Health Sciences Center, Thunder Bay, Ontario, Canada.
概括
心肌桥架 (MB) 和中度动脉样硬化显著增加心上的风险. 患有这两种疾病的患者患有的患病率最高,这突显了冠状动脉疾病的关键联系.
科学领域:
- 心脏病学 心脏病学
- 血管生物学 血管生物学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 之前的研究表明,心肌桥梁 (MB),动脉样硬化和心表血管之间存在单独的联系.
- 这些病症对冠状动脉功能的综合影响,特别是在北美,仍未得到充分研究.
研究的目的:
- 调查北美队列中心肌桥梁,中度动脉样硬化和心表的流行和相互作用.
- 确定MB和中度动脉样硬化是否是表心的独立风险因素.
主要方法:
- 侵袭性冠状动脉功能测试 (腺和乙胆诱导) 对472名患有心痛和非阻塞性冠状动脉的患者进行.
- 副心被定义为新的>90%的狭窄后乙胆.
- 评估了MB的存在和中度动脉样硬化 (>50%的狭窄或带负FFR的支架).
主要成果:
- 脊心发生在27.8%的患者中.
- 患有MB (43.7%) 和中度动脉样硬化 (39.6%) 的患者相比没有的患者,的发病率明显更高.
- 心上的患病率最高 (61.9%) 观察到的是患有MB和中度动脉样硬化症的患者.
结论:
- 心肌桥架和中度动脉样硬化独立地与心上的风险增加有关.
- 心血管最常见于表现为肌心桥架和中度动脉样硬化综合存在的个体.
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