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年龄和性别对左心室功能的影响,基于胸外心声图
Lu Tang1, Rui Wu1, Chen Cheng1
1Department of Cardiology, The First Affiliated Hospital with Nanjing Medical University, 210029 Nanjing, Jiangsu, China.
Reviews in cardiovascular medicine
|July 9, 2025
概括
年龄和性别显著影响左心室功能,即使在心脏结构正常的个体中也是如此. 监测这些变化对于了解不同人口的心脏健康至关重要.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 老年医学 老年医学
背景情况:
- 左心室 (LV) 功能评估对心血管健康至关重要.
- 了解 LV 功能的特定年龄和性别变化至关重要,特别是在没有结构性心脏病的个体中.
- 正常的心脏结构并不排除与年龄或性别相关的功能变化.
研究的目的:
- 为了研究左心室缩和放缩功能的与年龄和性别相关的差异.
- 在一个大型队列中,建立不同年龄,几十年和性别的LV功能参数的规范性数据.
- 在正常心脏结构的个体中识别LV功能改变的预测因素.
主要方法:
- 对10853个正常心脏结构的个体进行了回顾性分析.
- 从2017年至2020年间的跨胸腔心声学数据.
- 使用了内核密度估计,通用添加模型,相关性和多变量回归分析.
主要成果:
- 观察到年龄和射出分数 (EF) 之间存在显著的逆相关性 (B = -0.077,p < 0.001).
- 在所有年龄组中,女性的E/e'比率高于男性 (p < 0.001).
- 年龄在51.4岁以下的个体中是功能参数的更强有力的预测因素. 年龄和男性性别独立预测降低隔膜和侧面e'速度 (p < 0.001),男性显示较低的值.
结论:
- 这项研究在男性和女性的几十年年龄内提供了LV缩和透缩功能的全面分布.
- 强调监测心室功能的临床意义,即使在表面上是正常心脏结构的患者中也是如此.
- 强调需要针对年龄和性别的特定参考范围来确定LV功能的参数.
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