心脏热素T升高预测住院COVID-19患者的死亡率
Katelyn A Bruno1,2, R Scott Wright3, Joshua Culberson1,2
1Department of Cardiovascular Medicine, Mayo Clinic, Jacksonville, Florida.
高灵敏性心脏托波T (hs-cTnT) 水平预测住院COVID-19患者的死亡率. 这种预后能力适用于所有性别和年龄组,表明hs-cTnTT.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 生物标志物 生物标志物
背景情况:
- COVID-19可能会导致心脏损伤.
- 心脏中热素是心脏损伤的生物标志物.
- 预测COVID-19的结果至关重要.
研究的目的:
- 为了确定心脏中托波宁值是否预测COVID-19患者的不良结果.
- 在不同的人口统计数据中评估预后价值.
主要方法:
- 分析了高灵敏度的心脏托罗邦素T (hs-cTnT) 的水平.
- 包括1,050名重病住院的COVID-19患者.
- 在第一波疫情期间收集的数据.
主要成果:
- 观察到hs-cTnT水平与死亡率之间存在连续的关系.
- 这种关联在男性和女性中是一致的.
- 预后值独立于患者的年龄.
结论:
- hs-cTnT证明了住院COVID-19患者死亡率的预后能力.
- 在所有相关患者群体中,hs-cTnT是可靠的预测指标.
- 支持hs-cTnT在COVID-19风险分层中的使用.
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