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Updated: Sep 16, 2025

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在YAP/TAZ路径的基因组变化与干细胞类的割耐药前列腺癌相关

Marjorie L Roskes, Alexander Martinez-Fundichely, Sandra Cohen

    medRxiv : the preprint server for health sciences
    |July 9, 2025
    PubMed
    概括

    在YAP/TAZ路径中的基因组变异能够以79%的准确度预测类似干细胞的抵抗割的前列腺癌 (CRPC). 这项研究使用无细胞DNA (cfDNA) 全基因组测序 (WGS) 来揭示CRPC异质性,以改善患者分层.

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