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Updated: Apr 9, 2026

Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein
12:01

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在前突触终端的α-Synuclein-Assembled突触囊泡池:使用新型鼠标模型研究α-Synuclein功能

Chigure Suzuki1,2,3, Junji Yamaguchi1,4, Isei Tanida1

  • 1Department of Cellular and Molecular Neuropathology, Research Institute for Old Age, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo, 113-8421, Japan.

Acta histochemica et cytochemica
|July 9, 2025
PubMed
概括

阿尔法同核素 (SNCA) 与帕金森病有关. 使用转基因小鼠的新研究揭示了它在突触前终端突触囊泡形成中的作用,而不会导致运动缺陷或神经退行.

关键词:
在树脂中使用的CLEM.mKate2 的时间.突触囊泡池是一个突触囊泡池.转基因小鼠的转基因小鼠α-synuclein 是一种同核蛋白.

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