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相对脂肪量与心血管疾病之间的关联:基于NHANESES的横截面研究
Bin Zhang1,2, Changguo Zhu3, Lanhua Ma4
1Department of Hypertension and Vascular Disease, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Frontiers in cardiovascular medicine
|July 9, 2025
概括
相对脂肪量 (RFM) 是比传统措施更好的心血管疾病 (CVD) 风险指标. 较高的RFM水平显著增加了患心血管疾病的可能性,突出了其在预防策略中的潜力.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 肥胖问题研究研究
背景情况:
- 心血管疾病 (CVD) 是全球主要的死亡原因.
- 像BMI这样的传统肥胖指标在区分脂肪和肌肉方面存在局限性.
- 相对脂肪质量 (RFM),基于腰与身高的比率,是身体脂肪百分比的新指标.
研究的目的:
- 调查相对脂肪量 (RFM) 和心血管疾病 (CVD) 之间的关联.
- 评估RFM作为CVD风险评估的潜在指标.
主要方法:
- 使用国家健康和营养检查调查 (NHANES) 数据 (1999-2018) 的横截面研究.
- 包括45,000名参与者,不包括那些数据不完整的参与者.
- 使用多变量逻辑回归分析了RFM四分位数和心血管疾病患病率之间的关系.
主要成果:
- 在RFM和心血管疾病之间发现了显著的积极关联 (OR=1.04,P<0.001).
- 与最低四分位数 (P<0.001) 相比,最高RFM四分位数显示心血管疾病风险增加了2.11倍.
- 这种联系在年轻人 (<60岁),非西班牙裔白人和BMI<30 kg/m2的人中更为明显.
结论:
- 升高的RFM与心血管疾病的更高患病率有关.
- 电流管理可以成为预防和管理心血管疾病的宝贵工具.
- 需要进一步的前性研究来确认因果关系.
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