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Updated: May 6, 2026

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装配器:用于大DNA库的高通量装配的自动化工作流程

Antonio Vela Gartner, Luisa F Quispe, Klaus-Peter Rühmann

    bioRxiv : the preprint server for biology
    |July 9, 2025
    PubMed
    概括

    研究人员开发了改进的基于酵母的DNA组装方法,以更快,更便宜,更有效地合成高达50千基的大型DNA分子. 这些进展使得合成生物学和基因组工程中的高通量大DNA实验成为可能.

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    The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
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