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Updated: Sep 16, 2025

Visualization and Quantification of TGFβ/BMP/SMAD Signaling under Different Fluid Shear Stress Conditions using Proximity-Ligation-Assay
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Visualization and Quantification of TGFβ/BMP/SMAD Signaling under Different Fluid Shear Stress Conditions using Proximity-Ligation-Assay

Published on: September 14, 2021

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拉特罗菲林-2通过内分泌素和Shank3调节内皮细胞流介导的Smad1/5激活

Keiichiro Tanaka, Manasa Chanduri, Minghao Chen

    bioRxiv : the preprint server for biology
    |July 9, 2025
    PubMed
    概括

    液体剪切应力通过拉特罗菲林-2 (Lphn2) 和Shank3在内皮细胞中激活Smad1 / 5,独立于G蛋白信号传递. 这一途径对血管平衡至关重要,并可能影响周围动脉疾病风险.

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    A Microphysiological System to Study Leukocyte-Endothelial Cell Interaction during Inflammation

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