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Updated: Sep 16, 2025

Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay
07:10

Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay

Published on: September 14, 2014

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补充片段C3d的融合增强了生殖中心对HIV-1信封糖蛋白的反应

Marlon de Gast1,2, Sara Hernández-Pérez3, Arpan Pradhan4

  • 1Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

bioRxiv : the preprint server for biology
|July 9, 2025
PubMed
概括

将C3d融合添加到HIV-1 Env免疫原体中显著提高了生殖中心反应和抗原呈现,从而改善了小鼠的抗体产生和病毒中和.

关键词:
激活B细胞的激活过程联邦发行中心 (FDCs).艾滋病毒-1 Envv抗原的保留 抗原的保留补充 C3d 的补充.发芽中心的反应反应.中和抗体中和抗体.

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