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免疫挑战会影响生长动态,氧化应激和野生的无斑鸟幼的生存

Daniel Parejo-Pulido¹, Silvia Casquero¹, Ana Á Romero-Haro^1,2

¹Instituto de Investigación en Recursos Cinegéticos (IREC), CSIC-UCLM-JCCM, Ronda de Toledo 12, 13005 Ciudad Real, Spain.

The Journal of experimental biology

|July 9, 2025

概括

年轻鸟类的免疫挑战会影响生长,并导致氧化应激. 虽然没有斑点的鸟表现出快速的速度.

科学领域:

生态学和进化生物学.
动物生理学动物生理学

背景情况:

免疫系统的激活会产生显著的能量成本,影响生长和增加氧化应激.
由于持续的成熟和对生长的高资源需求,正在发展中的生物尤其容易受到伤害.

研究的目的:

调查野生无斑 (Sturnus unicolor) 幼中实验诱导的免疫挑战的生长和氧化应激成本.
确定幼是否可以补偿免疫诱导的生长成本,以及这些影响是否取决于条件.

主要方法:

实验性免疫挑战使用脂多糖 (LPS) 注射与对照 (PBS) 在种群内设计.
在治疗后8天内监测体重增加和生存率.
对血氧化损伤 (活性氧代谢物) 和抗氧化能力的分析.

主要成果:

免疫激活最初会影响体重增加,但在24小时内随之而来的是加速生长 ("追赶生长").
最初较小的挑战巢在第8天表现出减少的体重和生存率.
免疫挑战增加了血氧化损伤和抗氧化能力,表明氧化成本.

结论:

在生命早期建立免疫反应会产生与改变生长动态和增加氧化损伤相关的成本.
免疫挑战对生长和生存的影响取决于个体的初始状况.
幼表现出快速补偿生长的能力,但这可能无法完全减轻较小个体的长期成本.

关键词:

急性阶段的反应反应.其他地方.补偿性增长是一种补偿性增长.发展性可塑性发展性可塑性生命早期的发展.第二波离合器的第二波.

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