营养不良表明NPC患者的临床结果不佳:一个多中心队列研究
Yumin Wang1,2,3, Yongzhen Mo1,2, Mingxia Shuai1,2
1Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, China.
大多数鼻癌 (NPC) 患者营养不良,严重影响生存率. 早期营养评估和干预对于改善NPC患者的治疗结果至关重要.
科学领域:
- 在瘤学瘤学.
- 临床营养学 临床营养学
- 流行病学 流行病学
背景情况:
- 鼻癌 (NPC) 患者的营养状况尚不清楚.
- 缺乏关于NPC营养的大规模队列研究.
- 营养状况对于癌症治疗和治疗结果至关重要.
研究的目的:
- 调查鼻癌 (NPC) 患者的营养状况.
- 确定影响NPC患者存活率的临床风险因素.
- 突出营养支持在NPC管理中的重要性.
主要方法:
- 一个多中心,前性,横截面研究.
- 参与了1168名患有初级和复发性NPC的患者 (2013-2021年).
- 利用了中国常见癌症队列的营养状况调查及其临床结果的数据.
主要成果:
- 98%的NPC患者有营养不良的风险 (NRS2002得分).
- 营养不良 (PG-SGA评分≥9,BMI<18.5) 与不良的临床结果相关.
- 在患者中报告了显著的体重减轻和减少食物摄入量.
结论:
- 大多数NPC患者表现为营养不良.
- 营养不良是不良临床结果的重要预测因素.
- 营养评估和干预对于NPC患者的管理和监测至关重要.
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