阿雷卡坚果生产,进口及其对口腔癌发病率的影响
1State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
Journal of dental research
|July 9, 2025
概括
增加的地区坚果 (AN) 生产和进口与全球更高的唇部和口腔癌 (LOC) 率相关. 这凸显了需要采取类似于烟草控制的对AN消费的监管措施,以减轻公共卫生风险的必要性.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 唇部和口腔癌 (LOC) 占全球癌症负担的很大一部分,无烟烟草和阿雷卡坚果 (AN) 消费是主要的风险因素.
- 在过去的三十年中,全球坚果 (AN) 的生产和国际贸易大幅增加.
- 了解AN消费模式和LOC发病率之间的流行病学联系对于公共卫生干预至关重要.
研究的目的:
- 为了调查子 (AN) 产量和进口量变化与唇部和口腔癌 (LOC) 发病率之间的关联.
- 分析全球主要消费地区的AN生产,贸易和LOC发病率的趋势.
主要方法:
- 利用来自全球疾病负担和GLOBOCAN数据库的LOC发病率数据.
- 来自FAOSTAT和区域统计年鉴的地区坚果 (AN) 生产和进口数据.
- 使用斯皮尔曼的相关性分析来评估AN生产/进口和LOC发生率之间的关系.
主要成果:
- 在12个关键地区的Areca坚果 (AN) 产量从1990年到2021年增加了5.4倍.
- 在多个国家和整体中,在增加的AN产量和LOC发生率之间发现了强烈的正相关性 (R ≥ 0.8,P < 0.001).
- 在主要进口国家中,观察到年平均AN进口与LOC发生率之间的正相关性.
结论:
- 大规模的阿雷卡坚果 (AN) 生产与唇部和口腔癌 (LOC) 发病率的上升之间存在显著的正相关性.
- 阿拉卡坚果 (AN) 进口与LOC发病率的增加有关,这强调了全球贸易的影响.
- 建议对子 (AN) 制定监管策略,反映烟草控制措施,以解决这一日益严重的公共卫生问题.
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