全球处方模式和实践:在各国糖尿病管理中使用他类药物
Smruti Besekar1, Sangita Jogdand1, Satyawan Singh Patel2
1Department of Pharmacology, JNMC, DMIHER, Sawangi, Wardha, Maharashtra, India.
Indian journal of pharmacology
|July 9, 2025
概括
全球在2型糖尿病 (T2DM) 中使用的他类药物差异很大,高强度他类药物的使用不足和低风险患者的不适当处方. 改善准则的遵守对于降低心血管疾病 (CVD) 风险至关重要.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 心血管疾病 (CVD) 是2型糖尿病 (T2DM) 患者的主要并发症.
- 类药物对于T2DM患者的心血管疾病预防至关重要.
- 全球他类药物处方模式往往偏离临床指导方针,影响患者的治疗结果.
研究的目的:
- 审查T2DM治疗他类药物处方的全球趋势.
- 评估是否遵守临床指南,并确定他类药物使用的差距.
- 评估他类药物处方实践对T2DM心血管健康的影响.
主要方法:
- 系统审查遵循系统审查和元分析-2 (PRISMA-2) 准则的首选报告项目.
- 分析了8项研究,重点关注他类药物处方趋势,准则遵守和治疗强度.
- 在全球不同地区对他类药物的使用情况进行比较.
主要成果:
- 观察到,在全球范围内,他类药物处方率存在显著差异,亚洲的处方率高于非洲和一些发达国家.
- 在全球范围内,高强度他类药物使用量不足;许多患者接受了中度或低强度治疗.
- 在低风险T2DM患者中发生了不适当的他类药物处方,引发了对不良影响的担忧.
结论:
- 迫切需要改善对T2DM患者,特别是高危人群的他类药物指南的遵守.
- 必须通过加强医生教育和指导方针实施来解决最佳他类药物治疗的障碍.
- 优化他类药物治疗可以显著降低心血管疾病风险,并改善全球T2DM患者的治疗结果.
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