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Updated: May 7, 2026

Endothelial Cell Co-culture Mediates Maturation of Human Embryonic Stem Cell to Pancreatic Insulin Producing Cells in a Directed Differentiation Approach
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Endothelial Cell Co-culture Mediates Maturation of Human Embryonic Stem Cell to Pancreatic Insulin Producing Cells in a Directed Differentiation Approach

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从脂肪介质干细胞中获得的条件介质,用 pituitary adenylate cyclase-activating polypeptide (PACAP) 刺激,减轻RINm5F胰腺β细胞功能障碍

Aymé Oliva-Cárdenas1, Alejandro Ávalos-Rodríguez2, Guadalupe Díaz-Rosas3

  • 1Doctorado en Ciencias Biológicas y de la Salud, Universidad Autónoma Metropolitana, Ciudad de México, Mexico.

Molecular biology reports
|July 9, 2025
PubMed
概括

来自PACAP预先调节的介质介质介质介质细胞 (MSCs) 保护胰腺β细胞免受氧化损伤. 这种MSCs衍生的介质增强了细胞活力,减少了细胞亡,并恢复了胰岛素分泌,提供了潜在的治疗策略.

关键词:
有条件的介质介质.胰岛素分泌的胰岛素分泌.介质细胞层细胞是介质细胞层细胞.氧化应激是一种氧化应激.这就是PacaPap的意义.预先条件的形成在RINm5F中.

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Author Spotlight: Isolation and Identification of Mesenchymal Stem Cells Derived from Adipose Tissue of Sprague Dawley Rats10:50

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