相关实验视频
Updated: Sep 16, 2025

08:41
Modeling Chemotherapy Resistant Leukemia In Vitro
Published on: February 9, 2016
9.2K
儿童急性淋巴细胞白血病幸存者的睡眠障碍:一个横截面研究
Kanwaljeet Kaur Chopra1, Aditya Kumar Gupta2, Jagdish Prasad Meena1
1Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Indian pediatrics
|July 9, 2025
概括
儿童急性淋巴细胞白血病 (ALL) 幸存者经常经历睡眠障碍. 化疗期间的恐惧和治疗结束后的较短时间是这些睡眠问题的重要危险因素.
科学领域:
- 儿科瘤学 儿科瘤学
- 睡眠医学 睡眠医学
- 儿童癌症幸存率 儿童癌症幸存率
背景情况:
- 儿童癌症的幸存者面临着睡眠障碍的高风险,影响他们的整体幸福感.
- 儿童癌症幸存者的睡眠问题在整体护理方法中经常被忽视.
研究的目的:
- 为了确定儿童急性淋巴细胞白血病 (ALL) 幸存者的睡眠障碍的患病率.
- 为了确定与睡眠问题相关的风险因素,在这个人群中.
主要方法:
- 该研究招募了6至18岁的ALL幸存者,治疗至少在两年前完成.
- 儿童睡眠习惯问卷 (CSHQ) 被用于评估睡眠问题.
主要成果:
- 在研究的89名童年ALL幸存者中,42.7%的人报告睡眠障碍.
- 与睡眠问题显著相关的因素包括与治疗相关的恐惧,痛苦的记忆,入学时的年龄较小,治疗结束后的间隔较短.
结论:
- 几乎一半的童年 ALL 幸存者经历睡眠问题.
- 在化疗期间遇到的恐惧和治疗后较短的间隔成为睡眠障碍的重要风险因素.
相关概念视频
Nightmares and Night Terrors
166
Nightmares and night terrors represent two distinct types of sleep disturbances that differ in timing, characteristics, and the sleeper's recall of the event. Nightmares are vivid, disturbing dreams that usually awaken the sleeper from REM sleep, a stage of sleep where brain activity is high, and dreams are most frequent. Upon awakening, individuals often have detailed recollections of their nightmares, which can include themes of threats to survival, security, or self-esteem.
Nightmares...
Nightmares...
166
REM Sleep Behavior Disorder
425
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
RBD is significantly associated with...
425
Restless Leg Syndrome and Night Terrors
259
Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
259
Disorders of Leukocytes
1.2K
Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...
1.2K
Substance Use Disorders Affecting Sleep
225
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
225
Bone Marrow Sampling and Transplants
504
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
504

