没有患者标识符的记录链接:使用南非国家艾滋病毒计划数据的概念证明
Khumbo Shumba1, Jacob Bor1,2,3, Cornelius Nattey1
1Health Economics and Epidemiology Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
PLOS global public health
|July 9, 2025
概括
一种新的方法成功地将南非的健康数据库连接到没有患者标识符的HIV护理,从而提高了数据的完整性. 这种方法可以提高艾滋病毒计划的监测和患者数据的准确性,同时保持隐私.
科学领域:
- 公共卫生 公共卫生
- 医疗信息学 医疗信息学
- 流行病学 流行病学
背景情况:
- 健康数据库连接通常需要敏感的患者标识符.
- 南非公共部门的艾滋病毒计划在整合行政卫生数据方面面临挑战.
- 将TIER.Net和国家卫生实验室服务 (NHLS) 的数据结合起来,对于全面的艾滋病毒患者护理至关重要.
研究的目的:
- 开发和验证南非卫生数据库的无标识符记录链接策略.
- 将TIER.Net (艾滋病毒计划) 和NHLS (实验室) 数据与2015-2019年间埃库鲁勒尼区患者的数据联系起来.
- 评估连接策略的准确性和收益率,而不影响患者的隐私.
主要方法:
- 开发了一种使用结果值,样本采集日期,设施,出生日期和性别的顺序链接方法.
- 采用了精确匹配,口径匹配 (±5天) 和样本条形码匹配.
- 验证的链接策略与标本条形码作为黄金标准.
主要成果:
- 顺序链接实现了71.9%的测试结果匹配率,具有96.8%的正预测值 (PPV) 和85.9%的灵敏度.
- 成功将86.0%的TIER.Net患者与NHLS数据库联系起来.
- 在TIER.Net中增加了62.6%的实验室结果,提供了更完整的患者病史.
结论:
- 无标识符记录链接是可行和有效的,用于结合南非的健康数据库.
- 开发的战略实现了高准确性和产量,提高了艾滋病毒计划监测.
- 这种保护隐私的方法支持更准确的艾滋病毒计划指标估计和全面的患者护理.
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