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Updated: May 3, 2026

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由转基因小鼠产生的自主生物发光辐射

Kamila A Kiszka1, Christian Dullin2,3,4, Heinz Steffens1

  • 1Department of NanoBiophotonics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.

Science advances
|July 9, 2025
PubMed
概括

研究人员创造了一只转基因小鼠,它在不需要外部化学物质的情况下发光. 这一突破使得使用细菌生物发光技术实现了活哺乳动物的非侵入性实时成像.

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Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
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