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泛癌队列中的生殖系 POT1 变异

Pamela L Brock1, Morgan Webster2, Sandya Liyanarachchi3

  • 1Division of Human Genetics, The Ohio State University College of Medicine, Comprehensive Cancer Center, Columbus, OH.

JCO precision oncology
|July 9, 2025
PubMed
概括

生殖系POT1变种增加癌症风险,特别是慢性淋巴细胞白血病 (CLL) 和乳头甲状腺癌 (PTC). 这项针对庞大的胰腺癌队列的研究发现POT1变异与早期癌症诊断有关.

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