在严重的细胞外脱水和再适应期间,胸腺的结构组织
Olha Prykhodko1, Olga Avilova2, Serhii Dmytruk1
1SUMY STATE UNIVERSITY, SUMY, UKRAINE.
概括
严重的细胞外脱水会严重损害老鼠胸腺结构,用脂肪和结缔组织取代功能性组织. 胸腺结构和功能在补水后30天内无法完全恢复.
科学领域:
- 免疫学 免疫学 免疫学
- 身体生理学 身体生理学
- 历史学 历史学 历史学
背景情况:
- 细胞外脱水可以显著影响器官结构和功能.
- 胸腺是免疫系统发育和功能的一个关键器官.
研究的目的:
- 为了研究在长时间的细胞外脱水期间,大鼠胸腺的结构变化.
- 为了评估这些变化在补水期后的可逆性.
主要方法:
- 对大鼠胸腺组织进行了形态测量分析,组织学检查和免疫组织化学分析.
- 动物接受了90天的脱水,然后再进行30天的补水.
- 对照组在整个过程中都得到标准配给.
主要成果:
- 脱水导致了胸细胞核变形,细胞质损伤,亡,亡和血管血栓形成.
- 功能性胸腺组织在很大程度上被连接和脂肪组织所取代.
- 补水导致了部分胸腺恢复,增加了淋巴细胞密度,但持续的细胞压力和不完全的质量恢复的迹象.
结论:
- 严重的细胞外脱水会导致显著的甲状腺枯竭和血管封闭.
- 一个30天的补水期是不够的,以完全恢复甲状腺的形态和功能.
- 长时间的补水或其他干预措施可能是必要的,以完全恢复胸膜结构和功能.
相关概念视频
Primary Lymphoid Organs
6.9K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
6.9K
Renal Tubule and Collecting Duct
1.5K
The renal tubule is divided into three parts: the proximal convoluted tubule (PCT), the Loop of Henle (LOH), and the distal convoluted tubule (DCT).
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
1.5K
Secondary Lymphoid Organs
3.8K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
3.8K
Lymphoid Cells and Tissues
1.6K
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
1.6K
Accessory Structures of the Skin: Sweat Glands
2.5K
Sweat glands or sudoriferous glands are one of the important accessory structures of the skin. They are small, coiled tubular structures located in the dermis, the middle layer of the skin. Sweat glands are responsible for producing and secreting sweat, a watery fluid that helps regulate body temperature and excrete waste products.
Sweat glands are classified as merocrine glands; that is, the secretions are excreted by exocytosis through a duct without affecting the cells of the gland. There...
Sweat glands are classified as merocrine glands; that is, the secretions are excreted by exocytosis through a duct without affecting the cells of the gland. There...
2.5K
Cells of the Adaptive Immune Response
4.5K
The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
4.5K


