调节商业产母摄取和的成绩单的肠道分布在商业产母
Micaela Sinclair-Black1, R Alejandra Garcia-Mejia1, Camille Evans1
1Department of Poultry Science, University of Georgia, Athens, GA 30602, USA.
远端小肠和小肠在产母的和吸收中起着关键作用. 这项研究发现了对矿物运输的新见解,以改善蛋质量和骨健康.
科学领域:
- 动物科学动物科学
- 营养生理学 营养生理学
- 分子生物学分子生物学
背景情况:
- 和对于产母的蛋质量和骨完整性至关重要.
- 对于肠道矿物质吸收的荷尔蒙和载体机制尚未完全理解.
研究的目的:
- 为了研究与产卵母肠中的和同居关系的基因转录的分布.
- 为了确定关键的组织和携带器参与矿物质吸收.
主要方法:
- 用RT-qPCR分析产母的十二指肠,阴,阴茎和头骨中的mRNA表达.
- 从21周大的母和一个硬蛋中收集组织.
主要成果:
- 在所有组织中都发现了维生素D3代谢 (24-基酶,25-基酶) 的基因,其中在骨髓和骨中含量较高.
- 激素受体 (感受体,PTH1R,FGFRs) 的表达在小肠中偏远增加.
- 和运输体 (NCX1,PMCA2/4,TRPVs,PiT-1/2) 也在阴和阴茎中表达的增加.
- 肠内NCX1和PiT-1的表达明显高于小肠,这表明它在矿物质吸收中起着新的作用.
结论:
- 远端小肠和小肠对保持母的和平衡至关重要.
- 体代表了以前未被识别的显著和吸收的重要地点.
- 这些发现可以为优化食矿物质供应的策略提供信息,以提高健康和卵产量.
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