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Updated: Sep 16, 2025

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肺炎球菌脑膜炎的成年人中CSF转录组揭示了与死亡率相关的分隔宿主炎症反应

José Afonso Guerra-Assunção1, Probir Chakravarty2, Gabriele Pollara3

  • 1Research Department of Infection, Division of Infection and Immunity, University College London, UK; Erasmus University Medical Centre, Rotterdam, Netherlands.

Immunology letters
|July 9, 2025
PubMed
概括

肺炎球菌性脑膜炎 (PM) 造成严重的后果,特别是在非洲. 这项研究揭示了脑脊液 (CSF) 和血液中明显的炎症反应,脑脊液炎症与PM患者的死亡率更高有关.

关键词:
细菌性脑膜炎是一种脑膜炎.大脑脊髓液的脑脊液.艾滋病病毒 艾滋病病毒 艾滋病病毒伊尔-17 - 一个17岁的小孩.炎症 炎症是一种炎症.干扰素是干扰素的一种.死亡率 死亡率 死亡率作为一个中性粒细胞.蛋白质溶解是一种蛋白质溶解.肺炎链球菌的肺炎链球菌.

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